CD47

CD47
Structures disponibles
PDB	Recherche d'orthologue: PDBe RCSB
Identifiants PDB
	2JJS, 2JJT, 2VSC, 4CMM, 4KJY, 5IWL
Identifiants
Aliases	CD47
IDs externes	OMIM: 601028 MGI: 96617 HomoloGene: 1346 GeneCards: CD47
Position du gène (Homme)
Chr.	Chromosome 3 humain
Fin	108,091,862 bp
Position du gène (Souris)
Chr.	Chromosome 16 (souris)
Fin	49,735,373 bp
Expression génétique
	Fortement exprimé dans
	gingival epithelium; ; palpebral conjunctiva; ; germinal epithelium; ; pleura viscéral; ; right uterine tube; ; pancreatic epithelial cell; ; epithelium of nasopharynx; ; Brodmann area 23; ; tibia; ; pancreatic ductal cell;
	Fortement exprimé dans
	fetal liver hematopoietic progenitor cell; ; tibiofemoral joint; ; sang; ; medial dorsal nucleus; ; gyrus cingulaire; ; Corps géniculé latéral; ; nerf ischiatique; ; Vermis du cervelet; ; gastrula; ; rate;
	Plus de données d'expression de référence
	; ; ; ;
	Plus de données d'expression de référence
Gene Ontology
Fonction moléculaire	thrombospondin receptor activity; liaison protéique; protein binding involved in heterotypic cell-cell adhesion; cell-cell adhesion mediator activity;
Composant cellulaire	integral component of membrane; membrane plasmique; integral component of plasma membrane; membrane; specific granule membrane; tertiary granule membrane; exosome; surface cellulaire;
Processus biologique	integrin-mediated signaling pathway; positive regulation of phagocytosis; adhésion cellulaire; extracellular matrix organization; positive regulation of inflammatory response; positive regulation of T cell activation; response to bacterium; leukocyte migration; positive regulation of cell population proliferation; opsonisation; positive regulation of cell-cell adhesion; neutrophil degranulation; migration cellulaire; regulation of interferon-gamma production; regulation of interleukin-10 production; regulation of interleukin-12 production; regulation of interleukin-6 production; regulation of tumor necrosis factor production; heterotypic cell-cell adhesion; monocyte extravasation; regulation of nitric oxide biosynthetic process; positive regulation of stress fiber assembly; cellular response to interferon-gamma; cellular response to interleukin-1; cellular response to interleukin-12; cell-cell adhesion; negative regulation of Fc-gamma receptor signaling pathway involved in phagocytosis;
	Sources:Amigo / QuickGO
Orthologues
	961
	16423
	ENSG00000196776
	ENSMUSG00000055447
	Q08722
	Q61735
	NM_001025079; NM_001025080; NM_001777; NM_198793; NM_001382306
	NM_010581; NM_001368415; NM_001368416; NM_001368417; NM_001368418
	NP_001768; NP_942088; NP_001369235
	NP_034711; NP_001355344; NP_001355345; NP_001355346; NP_001355347
	Wikidata
Voir/Editer Humain	Voir/Editer Souris

Le CD47 est une protéine de type cluster de différenciation. Son gène, CD47 est situé sur le chromosome 3 humain.

↑ ^{a b et c} GRCh38: Ensembl release 89: ENSG00000196776 - Ensembl, May 2017
↑ ^{a b et c} GRCm38: Ensembl release 89: ENSMUSG00000055447 - Ensembl, May 2017
↑ « Publications PubMed pour l'Homme », sur National Center for Biotechnology Information, U.S. National Library of Medicine
↑ « Publications PubMed pour la Souris », sur National Center for Biotechnology Information, U.S. National Library of Medicine

[refGRCh38Ensembl-1] {a b et c} GRCh38: Ensembl release 89: ENSG00000196776 - Ensembl, May 2017

[refGRCm38Ensembl-2] {a b et c} GRCm38: Ensembl release 89: ENSMUSG00000055447 - Ensembl, May 2017

[3] « Publications PubMed pour l'Homme », sur National Center for Biotechnology Information, U.S. National Library of Medicine

[4] « Publications PubMed pour la Souris », sur National Center for Biotechnology Information, U.S. National Library of Medicine

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